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Although ICOS scientists were non examination combine IC351 for treating ED, they accepted its possible utility for treating that cark. Soon, in 1994, ICOS accepted a patent of invention for colonial IC351 (structurally unlike sildenafil citrate and vardenafil), and Phase 1 clinical trials began in 1995. In 1997, the Phase angle 2 clinical studies were initiated for males experiencing ED, and then progressed to the Stage 3 trials that supported the drug's Food and Drug Administration blessing.
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